Cochlear implantation for chronic electrical stimulation in the mouse.

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dc.contributor.authorIrving, Samuel
dc.contributor.authorTrotter, Matthew
dc.contributor.authorFallon, James
dc.contributor.authorMillard, Rodney
dc.contributor.authorShepherd, Robert
dc.contributor.authorWise, Andrew
dc.date.accessioned2014-12-01T23:25:15Z
dc.date.available2014-12-01T23:25:15Z
dc.date.issued2013-12
dc.description.abstractThe mouse is becoming an increasingly attractive model for auditory research due to the number of genetic deafness models available. These genetic models offer the researcher an array of congenital causes of hearing impairment, and are therefore of high clinical relevance. To date, the use of mice in cochlear implant research has not been possible due to the lack of an intracochlear electrode array and stimulator small enough for murine use, coupled with the difficulty of the surgery in this species. Here, we present a fully-implantable intracochlear electrode stimulator assembly designed for chronic implantation in the mouse. We describe the surgical approach for implantation, as well as presenting the first functional data obtained from intracochlear electrical stimulation in the mouse.en_US
dc.description.sponsorshipThis work was funded by NIH Contract HHS-N-263-2007-00053-C and by The Royal Victorian Eye and Ear Hospital. The Bionics Institute acknowledges the support it receives from the Victorian Government via its Operational Infrastructure Support Scheme.en_US
dc.identifier.citationIrving, S., Trotter, M. I., Fallon, J. B., Millard, R. E., Shepherd, R. K., Wise, A. K. (2013). Cochlear implantation for chronic electrical stimulation in the mouse. Hearing Research (306), pp. 37-45.en_US
dc.identifier.urihttp://repository.bionicsinstitute.org:8080/handle/123456789/97
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectCochlear Implanten_US
dc.subjectMouseen_US
dc.subjectChronic Electrical Stimulationen_US
dc.subjectFully Implantableen_US
dc.subjectProsthesisen_US
dc.subjectBionicen_US
dc.subjectOtotoxicityen_US
dc.titleCochlear implantation for chronic electrical stimulation in the mouse.en_US
dc.typeArticleen_US
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