neuroBi: A Highly Configurable Neurostimulator for a Retinal Prosthesis and Other Applications
| dc.contributor.author | Slater, Kyle | |
| dc.contributor.author | Sinclair, Nicholas | |
| dc.contributor.author | Nelson, Timothy | |
| dc.contributor.author | Blamey, Peter | |
| dc.contributor.author | McDermott, Hugh | |
| dc.date.accessioned | 2015-08-12T01:42:26Z | |
| dc.date.available | 2015-08-12T01:42:26Z | |
| dc.date.issued | 2015-07 | |
| dc.description.abstract | To evaluate the efficacy of a suprachoroidal retinal prosthesis, a highly configurable external neurostimulator is required. In order to meet functional and safety specifications, it was necessary to develop a custom device. A system is presented which can deliver charge-balanced, constant-current biphasic pulses, with widely adjustable parameters, to arbitrary configurations of output electrodes. This system is shown to be effective in eliciting visual percepts in a patient with approximately 20 years of light perception vision only due to retinitis pigmentosa, using an electrode array implanted in the suprachoroidal space of the eye. The flexibility of the system also makes it suitable for use in a number of other emerging clinical neurostimulation applications, including epileptic seizure suppression and closed-loop deep brain stimulation. Clinical trial registration number NCT01603576 (<uri xlink:href="www.clinicaltrials.gov" xlink:type="simple">www.clinicaltrials.gov</uri>). | en_US |
| dc.description.sponsorship | This work was supported in part by the Colonial Foundation, in part by the Bertalli Family Foundation, in part by the National Health and Medical Research Council under Grant 100764, and in part by the Australian Research Council through its Special Research Initiative in Bionic Vision Science and Technology grant to Bionic Vision Australia. The Bionics Institute acknowledge the support they receive from the Victorian Government through its operational infrastructure program. | en_US |
| dc.identifier.citation | Slater, K. D., N. C. Sinclair, T. S. Nelson, P. J. Blamey and H. J. McDermott (2015). neuroBi: A Highly Configurable Neurostimulator for a Retinal Prosthesis and Other Applications. IEEE Journal of Translational Engineering in Health and Medicine 3: e3800111. | en_US |
| dc.identifier.issn | 2168-2372 | |
| dc.identifier.uri | http://repository.bionicsinstitute.org:8080/handle/123456789/128 | |
| dc.language.iso | en | en_US |
| dc.publisher | IEEE | en_US |
| dc.subject | retinal prosthesis | en_US |
| dc.subject | neurostimulator | en_US |
| dc.subject | suprachoroidal | en_US |
| dc.subject | bionic vision | en_US |
| dc.subject | retinitis pigmentosa | en_US |
| dc.subject | electrode array | en_US |
| dc.title | neuroBi: A Highly Configurable Neurostimulator for a Retinal Prosthesis and Other Applications | en_US |
| dc.type | Article | en_US |