Halting the progression of noise-induced hearing loss with gene therapy
| dc.contributor.author | Richardson, Rachael | |
| dc.contributor.author | Atkinson, Patrick | |
| dc.contributor.author | Wise, Andrew | |
| dc.contributor.author | Flynn, Brianna | |
| dc.contributor.author | O'Leary, Stephen | |
| dc.contributor.author | Hume, Clifford | |
| dc.contributor.author | Shepherd, Robert | |
| dc.date.accessioned | 2013-08-28T05:14:29Z | |
| dc.date.available | 2013-08-28T05:14:29Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | Progressive hearing loss is often ignored until there is significant loss of cochlear hair cells (HCs) and spiral ganglion neurons (SGNs). It usually begins as a mild high-frequency threshold shift which worsens and also spreads to the lower frequencies. Our previous research indicated that gene therapy is effective for long-term preservation of SGNs when administered shortly after ototoxic hearing loss, but has greater potential to protect residual HCs and SGNs after the onset of progressive hearing loss and even to restore hearing. | en_US |
| dc.description.sponsorship | This study was generously funded by Action on Hearing Loss, the Garnett Passe and Rodney Williams Memorial Foundation and the National Health and Medical Research Council. The Bionics Institute acknowledges the support it receives from the Victorian Government through its Operational Infrastructure Support Program | en_US |
| dc.identifier.uri | http://repository.bionicsinstitute.org:8080/handle/123456789/43 | |
| dc.language.iso | en | en_US |
| dc.subject | Hearing Loss, Noise-Induced - Prevention & Control | en_US |
| dc.subject | Genetic Therapy - Methods | en_US |
| dc.title | Halting the progression of noise-induced hearing loss with gene therapy | en_US |
| dc.type | Presentation | en_US |