Development of a surgical procedure for implantation of a prototype suprachoroidal retinal prosthesis

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dc.contributor.authorSaunders, Alexia
dc.contributor.authorWilliams, Chris
dc.contributor.authorHeriot, Wilson
dc.contributor.authorBriggs, Robert
dc.contributor.authorYeoh, Jonathan
dc.contributor.authorNayagam, David
dc.contributor.authorMcCombe, Mark
dc.contributor.authorVillalobos, Joel
dc.contributor.authorBurns, Owen
dc.contributor.authorLuu, Chi
dc.contributor.authorAyton, Lauren
dc.contributor.authorMcPhedran, Michelle
dc.contributor.authorOpie, Nicholas
dc.contributor.authorMcGowan, Ceara
dc.contributor.authorShepherd, Robert
dc.contributor.authorGuymer, Robyn
dc.contributor.authorAllen, Penelope
dc.date.accessioned2015-09-21T05:20:39Z
dc.date.available2015-09-21T05:20:39Z
dc.date.issued2014-09
dc.description.abstractBACKGROUND: Current surgical techniques for retinal prosthetic implantation require long and complicated surgery, which can increase the risk of complications and adverse outcomes. METHOD: The suprachoroidal position is known to be an easier location to access surgically, and so this study aimed to develop a surgical procedure for implanting a prototype suprachoroidal retinal prosthesis. The array implantation procedure was developed in 14 enucleated eyes. A full-thickness scleral incision was made parallel to the intermuscular septum and superotemporal to the lateral rectus muscle. A pocket was created in the suprachoroidal space, and the moulded electrode array was inserted. The scleral incision was closed and scleral anchor point sutured. In 9 of the 14 eyes examined, the device insertion was obstructed by the posterior ciliary neurovascular bundle. Subsequently, the position of this neurovascular bundle in 10 eyes was characterized. Implantation and lead routing procedure was then developed in six human cadavers. The array was tunnelled forward from behind the pinna to the orbit. Next, a lateral canthotomy was made. Lead fixation was established by creating an orbitotomy drilled in the frontal process of the zygomatic bone. The lateral rectus muscle was detached, and implantation was carried out. Finally, pinna to lateral canthus measurements were taken on 61 patients in order to determine optimal lead length. RESULTS: These results identified potential anatomical obstructions and informed the anatomical fitting of the suprachoroidal retinal prosthesis. CONCLUSION: As a result of this work, a straightforward surgical approach for accurate anatomical suprachoroidal array and lead placement was developed for clinical application.en_US
dc.description.sponsorshipThis work was supported by the Australian Research Council through its Special Research Initiative in Bionic Vision Science and Technology awarded to Bionic Vision Australia and the Bertalli Family Foundation to the Bionics Institute. The Bionics Institute and CERA wish to acknowledge the support they receive from the Victorian Government through its Operational Infrastructure Program.en_US
dc.identifier.citationSaunders, A. L., C. E. Williams, W. Heriot, R. Briggs, J. Yeoh, D. A. Nayagam, M. McCombe, J. Villalobos, O. Burns, C. D. Luu, L. N. Ayton, M. McPhedran, N. L. Opie, C. McGowan, R. K. Shepherd, R. Guymer and P. J. Allen (2014). Development of a surgical procedure for implantation of a prototype suprachoroidal retinal prosthesis. Clinical & Experimental Ophthalmology 42(7): 665-674.en_US
dc.identifier.urihttp://repository.bionicsinstitute.org:8080/handle/123456789/132
dc.language.isoenen_US
dc.publisherJohn Wiley & Sons Incen_US
dc.subjectblindnessen_US
dc.subjectcadaveren_US
dc.subjectretinal prosthesisen_US
dc.subjectretinitis pigmentosaen_US
dc.titleDevelopment of a surgical procedure for implantation of a prototype suprachoroidal retinal prosthesisen_US
dc.typeArticleen_US
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