An update on retinal prostheses

dc.contributor.authorAyton, Lauren
dc.contributor.authorBarnes, Nick
dc.contributor.authorDagnelie, Gislin
dc.contributor.authorFujikado, Takashi
dc.contributor.authorGoetz, Georges
dc.contributor.authorHornig, Ralf
dc.contributor.authorJones, Bryan
dc.contributor.authorMuqit, Mahiul
dc.contributor.authorRathbun, Daniel
dc.contributor.authorStingl, Katarina
dc.contributor.authorWeiland, James
dc.contributor.authorPetoe, Matthew
dc.date.accessioned2020-01-06T04:44:35Z
dc.date.available2020-01-06T04:44:35Z
dc.date.issued2019-12
dc.description.abstractRetinal prostheses are designed to restore a basic sense of sight to people with profound vision loss. They require a relatively intact posterior visual pathway (optic nerve, lateral geniculate nucleus and visual cortex). Retinal implants are options for people with severe stages of retinal degenerative disease such as retinitis pigmentosa and age-related macular degeneration. There have now been three regulatory-approved retinal prostheses. Over five hundred patients have been implanted globally over the past 15 years. Devices generally provide an improved ability to localize high-contrast objects, navigate, and perform basic orientation tasks. Adverse events have included conjunctival erosion, retinal detachment, loss of light perception, and the need for revision surgery, but are rare. There are also specific device risks, including overstimulation (which could cause damage to the retina) or delamination of implanted components, but these are very unlikely. Current challenges include how to improve visual acuity, enlarge the field-of-view, and reduce a complex visual scene to its most salient components through image processing. This review encompasses the work of over 40 individual research groups who have built devices, developed stimulation strategies, or investigated the basic physiology underpinning retinal prostheses. Current technologies are summarized, along with future challenges that face the field.en_US
dc.identifier.citationAyton, L. N., N. Barnes, G. Dagnelie, T. Fujikado, G. Goetz, R. Hornig, B. W. Jones, M. M. K. Muqit, D. L. Rathbun, K. Stingl, J. D. Weiland, and M. A. Petoe. 2019. An update on retinal prostheses. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology: [epub ahead of print].en_US
dc.identifier.issn1388-2457
dc.identifier.urihttp://repository.bionicsinstitute.org:8080/handle/123456789/375
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.subjectRetinal prosthesisen_US
dc.subjectVision restorationen_US
dc.subjectRetinal diseaseen_US
dc.subjectOphthalmologyen_US
dc.titleAn update on retinal prosthesesen_US
dc.typeArticleen_US
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