Evaluation of focused multipolar stimulation for cochlear implants in acutely deafened cats

Simple item page
dc.contributor.authorGeorge, Shefin
dc.contributor.authorWise, Andrew
dc.contributor.authorShivdasani, Mohit
dc.contributor.authorShepherd, Robert
dc.contributor.authorFallon, James
dc.date.accessioned2015-11-09T04:50:23Z
dc.date.available2015-11-09T04:50:23Z
dc.date.issued2014-11
dc.description.abstractOBJECTIVE: The conductive nature of the fluids and tissues of the cochlea can lead to broad activation of spiral ganglion neurons using contemporary cochlear implant stimulation configurations such as monopolar (MP) stimulation. The relatively poor spatial selectivity is thought to limit implant performance, particularly in noisy environments. Several current focusing techniques have been proposed to reduce the spread of activation with the aim towards achieving improved clinical performance. APPROACH: The present research evaluated the efficacy of focused multipolar (FMP) stimulation, a relatively new focusing technique in the cochlea, and compared its efficacy to both MP stimulation and tripolar (TP) stimulation. The spread of neural activity across the inferior colliculus (IC), measured by recording the spatial tuning curve, was used as a measure of spatial selectivity. Adult cats (n = 6) were acutely deafened and implanted with an intracochlear electrode array before multi-unit responses were recorded across the cochleotopic gradient of the contralateral IC. Recordings were made in response to acoustic and electrical stimulation using the MP, TP and FMP configurations. MAIN RESULTS: FMP and TP stimulation resulted in greater spatial selectivity than MP stimulation. However, thresholds were significantly higher (p < 0.001) for FMP and TP stimulation compared to MP stimulation. There were no differences found in spatial selectivity and threshold between FMP and TP stimulation. SIGNIFICANCE: The greater spatial selectivity of FMP and TP stimulation would be expected to result in improved clinical performance. However, further research will be required to demonstrate the efficacy of these modes of stimulation after longer durations of deafness.en_US
dc.description.sponsorshipThis work was funded by The Garnett Passe and Rodney Williams Memorial Foundation. SSG was supported by an Australian Postgraduate Award through the Australian Government and a Bart Reardon Scholarship through the Bionics Institute. The Bionics Institute acknowledges the support it receives from the Victorian Government through its Operational Infrastructure Support Program.en_US
dc.identifier.citationGeorge, S. S., A. K. Wise, M. N. Shivdasani, R. K. Shepherd and J. B. Fallon (2014). Evaluation of focused multipolar stimulation for cochlear implants in acutely deafened cats. Journal of Neural Engineering 11(6): 065003.en_US
dc.identifier.urihttp://repository.bionicsinstitute.org:8080/handle/123456789/140
dc.language.isoenen_US
dc.publisherIOP Publishingen_US
dc.subjectCochlear implanten_US
dc.subjectElectrical stimulationen_US
dc.subjectMultipolar stimulationen_US
dc.subjectCurrent focusingen_US
dc.subjectInferior colliculusen_US
dc.titleEvaluation of focused multipolar stimulation for cochlear implants in acutely deafened catsen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
2015-11 George-FocusedMultipolarStimulation.pdf
Size:
802.49 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
BI publications