A comprehensive characterization of cognitive performance, clinical symptoms, and cortical activity following mild traumatic brain injury (mTBI).

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dc.contributor.authorCoyle, Hannah L
dc.contributor.authorBailey, Neil W
dc.contributor.authorPonsford, Jennie
dc.contributor.authorHoy, Kate E
dc.date.accessioned2024-04-12T03:19:53Z
dc.date.available2024-04-12T03:19:53Z
dc.date.issued2023-11-28
dc.description.abstractThe objective of this study was to investigate clinical symptoms, cognitive performance and cortical activity following mild traumatic brain injury (mTBI).
dc.description.abstractWe recruited 30 individuals in the sub-acute phase post mTBI and 28 healthy controls with no history of head injury and compared these groups on clinical, cognitive and cortical activity measures. Measures of cortical activity included; resting state electroencephalography (EEG), task related EEG and combined transcranial magnetic stimulation with electroencephalography (TMS-EEG). Primary analyses investigated clinical, cognitive and cortical activity differences between groups. Exploratory analyses investigated the relationships between these measures.
dc.description.abstractAt 4 weeks' post injury, mTBI participants exhibited significantly greater post concussive and clinical symptoms compared to controls; as well as reduced cognitive performance on verbal learning and working memory measures. mTBI participants demonstrated alterations in cortical activity while at rest and in response to stimulation with TMS.
dc.description.abstractThe present study comprehensively characterized the multidimensional effect of mTBI in the sub-acute phase post injury, showing a broad range of differences compared to non-mTBI participants. Further research is needed to explore the relationship between these pathophysiologies and clinical/cognitive symptoms in mTBI.
dc.identifier.citationCoyle, H. L., Bailey, N. W., Ponsford, J., & Hoy, K. E. (2023). A comprehensive characterization of cognitive performance, clinical symptoms, and cortical activity following mild traumatic brain injury (mTBI). Applied Neuropsychology: Adult, 1–17. https://doi.org/10.1080/23279095.2023.2286493
dc.identifier.urihttps://repository.bionicsinstitute.org/handle/123456789/450
dc.language.isoen
dc.publisherApplied Neuropsychology: Adult
dc.subjectMild traumatic brain injury (mTBI;)
dc.subjectcognition
dc.subjectelectroencephalography (EEG)
dc.subjectpathophysiology
dc.subjectpost-concussion symptoms
dc.subjecttranscranial magnetic stimulation (TMS)
dc.titleA comprehensive characterization of cognitive performance, clinical symptoms, and cortical activity following mild traumatic brain injury (mTBI).
dc.typeArticle
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