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Title: Halting the progression of noise-induced hearing loss with gene therapy
Authors: Richardson, Rachael
Atkinson, Patrick
Wise, Andrew
Flynn, Brianna
O'Leary, Stephen
Hume, Clifford
Shepherd, Robert
Keywords: Hearing Loss, Noise-Induced - Prevention & Control
Genetic Therapy - Methods
Issue Date: 2013
Abstract: Progressive hearing loss is often ignored until there is significant loss of cochlear hair cells (HCs) and spiral ganglion neurons (SGNs). It usually begins as a mild high-frequency threshold shift which worsens and also spreads to the lower frequencies. Our previous research indicated that gene therapy is effective for long-term preservation of SGNs when administered shortly after ototoxic hearing loss, but has greater potential to protect residual HCs and SGNs after the onset of progressive hearing loss and even to restore hearing.
URI: http://repository.bionicsinstitute.org:8080/handle/123456789/43
Appears in Collections:Bionic Hearing Conference Posters

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