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Title: Evaluation of stimulus parameters and electrode geometry for an effective suprachoroidal retinal prosthesis
Authors: Shivdasani, Mohit
Luu, Chi
Cicione, Rosemary
Fallon, James
Allen, Penny
Leuenberger, James
Suaning, Gregg
Lovell, Nigel
Shepherd, Robert
Williams, Chris
Issue Date: 2010
Publisher: IOP Publishing Ltd
Citation: Shivdasani, M. N., Luu, C. D., Cicione, R., Fallon, J. B., Allen, P. J., Leuenberger, J., ... & Williams, C. E. (2010). Evaluation of stimulus parameters and electrode geometry for an effective suprachoroidal retinal prosthesis. Journal of neural engineering, 7(3), 036008.
Series/Report no.: 7;3
Abstract: Several approaches have been proposed for placement of retinal prostheses; epiretinal, sub-retinal, and suprachoroidal. We aimed to systematically evaluate the effectiveness of varying a range of stimulus parameters and electrode geometry for a suprachoroidal electrode array, using cortical evoked responses to monopolar electrical stimulation in cats. Our results indicate that charge thresholds were not dependent on electrode size, pulse widths or position of the return electrode tested, but were dependent on the number of sites stimulated in parallel. Further, we found that the combination of monopolar stimulation with large diameter electrodes, wide pulse widths and parallel stimulation minimized the voltage requirements for stimulation. These results provide useful insights for the design specifications of a low voltage suprachoroidal stimulator.
URI: http://repository.bionicsinstitute.org:8080/handle/123456789/192
ISSN: 1741-2560
Appears in Collections:Bionic Vision Research Publications

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